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Visible reflectance spectroscopy to observe the effect of copper embedded socks on erythema in feet
(University of Missouri--Columbia, 2008)
Objective assessment of skin characteristics is necessary to aid in the clinical detection of erythema and debilitating skin conditions. The ability to treat different skin pathologies based on individual patient skin ...
Detection of CD4 and CD8 t-lymphocytes and HER2 breast cancer biomarker using the opto-fluidic ring resonator biosensor
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] We have demonstrated label-free detection of CD4+ and CD8+ T-Lymphocytes and HER2 breast cancer biomarker using the opto-fluidic ring resonator (OFRR) sensor. The OFRR sensing...
Regulation of calcium signaling by p130PH in astrocytes
(University of Missouri--Columbia, 2009)
Ca2+ signaling is a characteristic form of astrocyte excitability, but its role in ischemia is not clearly understood. Our previous study (Ding et al., 2009) demonstrated that astrocytes exhibit enhanced Ca2+ signaling following photothrombosis...
Knee contact force prediction during a step-up task using a subject specific musculoskeletal model with anatomical knee
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Better understanding of knee mechanics can aid in injury prevention and rehabilitation. Multi-body computational models can be used to better understand the knee mechanics...
Modeling the impact of polystyrene microparticles on toxicity of phenol to Artemia
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The increasing use and availability of micro and nanoparticles for use in science, technology and daily consumer products has led to unique challenges related to understanding...
Aptamer encoded nanopores as single molecule sensors
(University of Missouri--Columbia, 2008)
protein molecule detection for medical and biothreat applications. One of the exciting observations is a single restriction enzyme (Hind III) activity within nano-confinement. The duration of event could indicate the strength of the interaction...
Accurate DNA microsatellite and microRNA detection with a biological nanopore
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Nanopore-based detection has been used in many genetic, epigenetic, proteomic, and bio-mechanism studies. In this report, we introduced two designed strategies...
Study of human pupillary light reflex and its potential application in autism
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pupillary light reflex (PLR) can be used as an objective and non-invasive method to evaluate certain brain functions. In this research, we developed a binocular pupillogram...
Single nucleotide polymorphism (SNP) discriminations by nanopore sensing
(University of Missouri--Columbia, 2018)
Single Nucleotide Polymorphisms (SNPs) are a common type of nucleotide alterations across the genome. A rapid but accurate detection of individual or SNP panels can lead to the right and in-time treatments which possibly ...
Manure management using precision agriculture
(University of Missouri--Columbia, 2010)
The overall purpose of this project was to develop and implement a manure application record system that was solely based on Global Positioning Systems (GPS). This system will have the ability to provide steering and ...
Development and applications of label-free optofluidic ring resonator biosensor
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This dissertation presents the development and applications of label-free optofluidic ring resonator (OFRR) sensor platform. The OFRR sensor naturally integrates the optical...
Time delay compensation in finite-order models of acoustic wave propagation in homogenous media
(University of Missouri--Columbia, 2011)
Finite-order models do not completely account for the delay in acoustic wave propagation and thus require an additional phase correction, besides parameter adjustments to fit experimental measurements. As a consequence, ...
Synthesis and application of semiconductor quantum dots in novel sensing applications
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis details the synthesis of CdSe/ZnS semiconductor nanocrystals (quantum dots). These quantum dots (QDs) show very interesting optical properties of broadband excitation...
Development of an online planning tool for designing terrace layouts
(University of Missouri--Columbia, 2010)
A web-based conservation planning tool for terrace layouts was created by modifying a terrace location program (TERLOC), developed originally by Sudduth and Gregory (1982) and revised by Ghidey et al. (1992). Development ...
Automatic four-limb IMU gait analysis in the canine DMD model
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Gait analysis is valuable for studying neuromuscular and skeletal diseases. Wearable motion sensors or inertial measurement units (IMUs) possess advantages that have made them...
Engineering target nanomaterials for stable and efficient delivery of siRNA
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Lung cancer has the highest cancer-related mortality rate in the United States. The most common form of lung cancer is non-small cell lung cancer (NSCLC) with 80...
Modeling of delayed fluorescence from photosystem II and applications in assessment of drought and chemical stresses
(University of Missouri--Columbia, 2009)
Photosynthesis is not only vital for plant growth and survival but also indicative of plant-environment interactions. This research was designed to analyze photoelectron kinetics and its dependence on environmental factors. ...
Targeted therapeutics for non small cell lung carcinoma
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "Lung carcinoma, also known as lung cancer, is a malignant tumor of lungs characterized by uncontrolled call growth in lung tissue. Tobacco smoking is the reason for nearly 85...
Climate and land use effects on hydrologic processes and water allocation in a primarily rain-fed, agricultural watershed
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] There is a need to raise our understanding of the impact of climate variability and change on hydrologic processes at the watershed scale. This is important, particularly...
Design and synthesis of targeted NIR fluorescent nanoparticles for bio-imaging
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Breast cancer is the second most common cancer, and the chance that a woman will die from breast cancer is 2.6%. One in 8 women develop breast cancer during...